Candidiasis of the lungs

- damage to the bronchi and lungs caused by yeast-like fungi of the genus Candida.

The etiology and pathogenesis of Candidiasis of the lungs

Candida fungi-saprophytes that live on the skin and mucous membranes of humans, have a pathogenic effect when weakening the immunobiological protection of the body (in chronic diseases, beriberi, prolonged use of antibiotics, immunosuppressants).

Lung candidiasis is a secondary disease that occurs against the background of bacterial and viral pneumonia, tuberculosis, suppuration, and deep granulocytopenia; it is characterized by tenacious pneumonic foci with necrosis in the center and fibrinous effusion in the alveoli that surround the necrosis zone. The bronchial wall may also become necrotic. The outcome of the disease is the formation of purulent cavities or fibrosis of the lungs.

Symptoms and courseCandidiasis of the lungs

Fever, shortness of breath, tachycardia, chest pain, agonizing cough with the release of scanty mucous sputum, sometimes with streaks of blood, bronchospastic syndrome. On radiographs, there are spotty shadows, more intense areas of darkening, less often pleural effusion.

DiagnosisCandidiasis of the lungs

Confirmed by the detection of budding cells and mycelium of fungi in sputum, feces, urine, growth of fungi in seeding on special media.

TreatmentCandidiasis of the lungs

Nystatin 4 000 000 - 6 000 000 ED / day inside repeated 10-14-day courses with an inter Val 2-3 weeks; levorin - 1 500 000 ED/day repeated 10-12-day courses with an interval between them 5-7 days; amphotericin in / in drip for 46 hours in a single dose of 250 ED / kg (daily dose no more than 1000 ED/kg) every other day or 2-3 times a week for 48 weeks, the total course dose 1 500 000 - 2 000 000 ED. Prescribe iodine preparations, vitamins C and b, and other General tonic agents.